Cell tracking in vivo by optical imaging strategies
Jorg Hamm
jorg_hamm@yahoo.com

 

Description

- design of reporter genes for optical imaging applications
- generation of cell lines expressing reporter genes
- generation of transgenic mice expressing reporter genes
- cell tracking of labeled cells by in vivo imaging
- imaging of inflammatory reactions with fluorescent contrast agents
- non invasive monitoring of tumor growth and response to therapeutic treatment

 

Selected publications

Cerchia L, Hamm J, Libri D, Tavitian, B, de Franciscis V (2002)
Nucleic acid aptamers in cancer medicine.
FEBS Lett. 528:1-3, 12-6

Benedetto S, Pulito R, Crich SG, Tarone G, Aime S, Silengo L, Hamm J. (2006)
Quantification of the expression level of integrin receptor alpha(v)beta3 in cell lines and MR imaging with antibody-coated iron oxide particles.
Magn Reson Med. 56, 711-6

Chauveau F, Aissouni Y, Hamm J, Boutin H, Libri D, Ducongé F, Tavitian B. (2007)
Binding of an aptamer to the N-termianal fragment of VCAM1
Bioorg. Med. Chem. Lett.17:22, 6119-22

Hamm J, Pulito R, Benedetto S, Barberis L, Hirsch E, Poli V, Silengo L (2008)
Magnetically enriched bone marrow-derived macrophages loaded in vitro with iron oxide can migrate to inflammation sites in mice
NMR in Biomedicine 21: 120-128 (Electronic publication ahead of print: 2007 May 14)

Sbroggiò M, Ferretti R, Percivalle E, Gutkowska M, Zylicz A, Michowski W, Kuznicki J, Accornero F, Pacchioni B, Lanfranchi G, Hamm J, Turco E, Silengo L, Tarone G, Brancaccio M (2008)
The mammalian CHORD-containing protein melusin is a stress response protein interacting with Hsp90 and Sgt1
FEBS Lett. 582: 1788-179

 

Unit members

Pulito
Roberta
      

roberta.pulito@unito.it

 

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