Giovanni Camussi Normal and tumor-derived resident stem cells in human tissues Telephone: Fax: E-mail: giovanni.camussi@unito.it

CURRICULUM VITAE            Prof. Giovanni Camussi M.D.   Date of birth:                            26 August, 1947 Place of birth:                           Torino, Italy Academic appointments:          Full Professor, University of Torino   PROFESSIONAL BACKGROUND: 1973-1975: Post-doctoral fellow, Chair of Nephrology, University of Torino, Italy 1975-76: "Stagiare de recherches" at the INSERM U-25, Hopital Necker, Paris,  France 1976-80 and 1982-84: Assistant Professor of Nephrology and Head of the Renal Immunopathology Laboratory at the University of Torino, Italy. 1980, 82: Research Associate in the Department of Pathology, State University of New York, Buffalo NY, USA 1984-87: Associate Professor of Microbiology and Pathology, State University of New York, Buffalo NY, USA. 1988-94: Full Professor in the Department of Biochemistry and Biophysics at the II University of Naples, Italy. 1994-1998: Full Professor in the Department of Clinical and Biological Sciences, Chair of Nephrology and Clinical Immunology, II Faculty of Medicine, Varese, University of Pavia. 1998-present: Full professor in the Department of Internal Medicine, Chairman of Nephrology, Faculty of Medicine and School of Biotechnology, University of Torino, Italy,   -Prof. G. Camussi, has been Director of the Department of Internal Medicine and Director of the PhD programme in Medical Pathophysiology of the University of Torino.   -He is Director of the Laboratory of Renal and Vascular Pathophysiology of the Department of Internal Medicine, of the Stem Cell Laboratory of Molecular Biotecnology Center and of the Laboratory of Vascular Biology and Angiogenesis of the Research Center for Experimental Medicine (CeRMS).   -He is the President of the University School of Medical Biotechnology, and Director of the PhD program in Complexity in Medicine and Life Science, University of Torino.   SCIENTIFIC ACTIVITY:  Main lines of research: studies on  mediators of inflammation with particular regards to the biochemical characterization, the cellular origin and the biological activities of platelet-activating factor (PAF); studies on the pathophysiological role of complement components with particular regards to C5a and C3a-desArg and terminal component of complements; studies on the biological effect of  proinflammatory cytokines with particular regard to TNF; studies on the biological role of neutrophils and platelet-derived cationic proteins in inflammation; studies on the molecular mechanisms involved in leukocyte-endothelial interaction; studies on the immune mechanisms involved in renal and lung injury with particular regards to circulating and in situ formed immune-complexes; development of a model of antibody-mediated endothelial injury of the lung; studies on the mediators involved in the progression of renal injury; studies on  mediators and receptors involved in septic shock; studies on mediators involved on tumor angiogenesis. In this field, he contributed to the definition of some pathogenic mechanisms involved in neoangiogenesis with particular regards to the angiogenic mechanism of TNF, PAF and HGF. Currently, he is interested in the role of bone-marrow derived or resident stem cells in renal tissue regeneration as well as in the molecular mechanisms driving stem cell recruitment and differentiation. Moreover, he is working on the pathogenesis of diabetic nephropathy.     Prof Camussi has been the principal investigator in research projects funded by both national (Health Institute, Italian Association for Cancer Research, Italian Association for Research on Stem Cells, Italian Ministry of Education, University, and Research) and European (Kistem Project, European 6th Framework Programme on Research, Technological Development and Demonstration, and Marie Curie Actions; Nanotechnology) funding agencies.       -He served as referee for the following journals: Journal Experimental Medicine, Jounal of Cellular and Molecular Medicine, Journal Molecular Medicine, International Journal of Molecular Medicine, Kidney International, Journal of Nephrology, Blood, Journal of Immunology, Critical Care Medicine, The American Journal of Pathology, The Journal of American Society of Nephrology, Nature Medicine, Circulation, Circulation Research, International Journal of Cancer, Cancer Research. - He served as referee for the following research agencies: Wellcome Trust (UK); Cancer Research UK; Canadian Institutes of Health Research; German Federal Ministry of Education and Research,  Ministero Istruzione Università e Ricerca, Istituto Superiore di Sanità, Swiss National Science Foundation. . Prof. G. Camussi is author of 378 publications on PubMed indexed journals. ISI Web of Knowledge Citation Report from 1990: h-index = 41